Microbes and Infection
Volume 17, Issue 2, February 2015, Pages 142-148
Tianlei Ying, Haoyang Li, Lu Lu, Dimiter S. Dimitrov, Shibo Jiang
Abstract
The recent Middle East respiratory syndrome coronavirus (MERS-CoV) outbreak poses a serious threat to public health. Here, we summarize recent advances in identifying human neutralizing monoclonal antibodies (mAbs) against MERS-CoV, describe their mechanisms of action, and analyze their potential for treatment of MERS-CoV infections.
Keywords
Coronavirus, MERS-CoV, mAbs, Receptor binding domain (RBD)