Chinese Medical Journal
Gao, Hui-Xia; Li, Ya-Nan; Xu, Zun-Gui; Wang, Yu-Ling; Wang, Hai-Bin; Cao, Jin-Feng; Yuan, De-Qin; Li, Li; Xu, Yi; Zhang, Zhi; Huang, Ying; Lu, Jian-Hua; Liu, Yu-Zhen; Dai, Er-Hei.
Abstract
To The Editor: The epidemic caused by 2019 novel coronavirus (2019-nCoV) has drawn public attention. Huge infected population and enormous economic loss make it the urgent public health event to deal with. Confirmatory test targeting virus RNA was established at the early stage of outbreak and then used for 2019-nCoV infection diagnosis. However, high risk of laboratory infection, high-qualified personnel and strict operation condition hampered its application into primary hospitals and community clinics. In this study, the serum immunoglobulin (Ig) M and IgG antibodies were detected in 2019-nCoV confirmed cases of different stages. Furthermore, three different immunological assays, chemiluminescent immunoassay (CLIA), gold immunochromatographic assay (GICA), and enzyme-linked immunosorbent assay (ELISA) were used for IgM and IgG detection.
Keywords
Clinical aspects, diagnosis, treatment