COVID-19: faecal-oral transmission?

Nature reviews. Gastroenterology & hepatology

Hindson, J.

Research Highlights

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, which causes coronavirus disease 2019 (COVID-19), first emerged in China in December 2019 and has now spread worldwide, with a reported 351,731 confirmed cases and 15,374 deaths as of 23 March 2020 according to John Hopkins University. The infection is typically characterized by respiratory symptoms, which indicates droplet transmission.

Keywords

COVID-19, SARS-CoV-2, Treatment

Correction To: COVID-19: A Novel Coronavirus And A Novel Challenge For Critical Care

Intensive Care Medicine

Arabi, Y. M.; Murthy, S.; Webb, S.

Introduction

The original version of this article unfortunately contained a mistake. There was an error in table one: in the last row, second column the part “Still being defined to” should be crossed out. The correct Table 1 can be found below. We apologize for the mistake.

Keywords

Clinical aspects, diagnosis, treatment

Prevalence of comorbidities in the Middle East respiratory syndrome coronavirus (MERS-CoV): a systematic review and meta-analysis

International Journal of Infectious Diseases
Volume 49, August 2016, Pages 129-133

Alaa Badawi, Seung Gwan Ryoo

Abstract

The Middle East respiratory syndrome coronavirus (MERS-CoV) is associated with life-threatening severe illnesses and a mortality rate of approximately 35%, particularly in patients with underlying comorbidities. A systematic analysis of 637 MERS-CoV cases suggests that diabetes and hypertension are equally prevalent in approximately 50% of the patients. Cardiac diseases are present in 30% and obesity in 16% of the cases. These conditions down-regulate the synthesis of proinflammatory cytokines and impair the host's innate and humoral immune systems. In conclusion, protection against MERS-CoV and other respiratory infections can be improved if public health vaccination strategies are tailored to target persons with chronic disorders.

Keywords

Diabetes mellitus, Cardiovascular diseases, Obesity, Middle East respiratory syndrome coronavirus (MERS-CoV), Systematic review

Middle East respiratory syndrome coronavirus (MERS-CoV): challenges in identifying its source and controlling its spread

Microbes and Infection
Volume 15, Issues 8–9, July–August 2013, Pages 625-629

Lu Lu, Qi Liu, Lanying Du, Shibo Jiang

Abstract

Middle East respiratory syndrome coronavirus (MERS-CoV), a novel human coronavirus that caused outbreaks of a SARS-like illness in the Middle East, is now considered a threat to global public health. This review discusses the challenges in identifying the source of this fatal virus and developing effective and safe anti-MERS-CoV vaccines and therapeutics in order to control its spread and to combat any future pandemic.

Keywords

Coronavirus, MERS-CoV, SARS-CoV, Source, Vaccine, Therapeutics